PO-02-010 CRT COULD NOT MODIFY THE ARRHYTHMIC SUBSTRATE IN PATIENTS WITH PREVIOUS VENTRICULAR TACHYCARDIA/FIBRILLATION

Patients with low cardiac function are at high risk for ventricular arrhythmia (VA). Previous studies showed that resynchronization therapy (CRT) improved left remodeling and CRT responder had lower of VA than non-responder. However, little is known about the among or without history VA. The purpose this study to investigate association between response patients Among our cohort 497 consecutive patients, we retrospectively investigated 351 which included primary secondary prevention Exclusion criteria was hemodialysis, date deficit ejection fraction volume. defined as lasted ≥ 30s treated by anti-tachycardia pacing shock. responders 15% decrease in end-systolic volume increase 10% after implantation. Two hundred forty were (68.4%), 70 indication (19.9%). During a follow-up 901 days (inter quartile range: 365-1737) 93 events (CRT responder: 55pts, non-responder: 38pts). Kaplan-Meier analysis non-responder all (log rank p=0.003) p=0.004), though there no significant difference patient p=0.695). In addition, multivariate independent predictor (hazard ratio 0.50; 95% confidence interval 0.29-0.84, p=0.009), not (p=0.83) remain even responders. could reduce substrate.